France striker Djibril Cisse is out of the World Cup after breaking his right leg in the friendly against China on Wednesday.
The 24-year-old fell awkwardly 10 minutes into the game, his leg twisting under him and buckling above the ankle.
Cisse had immediate surgery on a fractured tibia.
France coach Raymond Domenech said: “He has an open fracture of the tibia.
“It’s a vicious blow to all of us.”
Cisse, who broke his left leg while playing for Liverpool in October 2004, had been linked with a move to Marseille after the World Cup.
Fenerbahce striker Nicolas Anelka or Barcelona’s Ludovic Giuly are in line to replace Cisse in the French squad.
Domenech said: “We don’t know the name of his replacement yet, we want to take our time in order to make the right decision.
“This is a big shock and a huge trauma for the team.”
During qualification for the finals Cisse was France’s leading scorer with four goals.
