Inter v Anderlecht
Inter are already ensured of qualification, but will be keen to take maximum points in front of their home crowd, and qualify top of Group G.
Anderlecht are already out of the competition, and even the consolation of a place in the UEFA Cup is beyond them.
“We care about finishing first in the group even if, watching how things are going in the other groups, perhaps it might be better to finish second,” said Inter coach Roberto Mancini. “You always have to go out and play to win.”
Some changes are expected as Mancini may rest key players but the coach said: “Whoever goes out there will put on an excellent performance.”
Adriano is suspended, so strike partner Christian Vieri looks set to start with Obafemi Martins.
Juan Sebastian Veron is also likely to be left out, whilst Kily Gonzalez, Emre and Alberto Fontana are injured.
Mancini will rest several players, but Edgar Davids and Marco Materazzi are both likely to feature.
Anderlecht coach Hugo Broos said: “It is a very important game even if we are already eliminated.
“Our pride is at stake since we don’t want to finish without any points. Our players will go out and give 100 per cent for the team.”
Broos will be without Czech keeper Daniel Zitka who broke his arm in training.
Zitka will join Glen de Boeck on the sidelines.