The French league leaders were the victims of a huge giant-killing act.
Fourth division Grenoble caused a massive shock in the French Cup, knocking out league leaders Marseille on penalties in the round of 64.
Selim Bengriba scored an injury-time equaliser for the minnows as the game ended 3-3 after extra time, and Mourad Nasrallah then scored the decisive spot-kick as the hosts won 5-4 on penalties.
Gasan Magomedov, a 20-year-old midfielder with Russian club Anzhi, was shot dead while driving near his home in Russia’s North Caucasus.
His car was hit by machine-gun fire and he died from his wounds while being transported to hospital.
Anzhi have been title challengers in recent years but were relegated last season after billionaire owner Suleyman Kerimov withdrew his financial backing.
For several years the club were based in Moscow due to security risks in their home town of Makhachkala in the region of Dagestan, which has been the focus of militant activity in the North Caucasus.