Nemanja Vidic has been ruled out of Manchester United’s Champions League encouter with Milan.
The Serbian defender were not included in the squad that flew to Milan on Monday morning ahead of Tuesday’s clash.
Vidic, who has developed a nerve problem in his leg, has yet to play in 2010.
It means United boss Sir Alex Ferguson must decide between Jonny Evans or Wes Brown to partner Rio Ferdinand at the heart of the defence.
Otherwise United have no other injury problems to contend with as they look to gain a positive result to bring back to Old Trafford for the second leg.