Roma travel to Madrid looking to overcome a 2-0 deficit, but after seven successive Serie A wins, confidence is high for Luicano Spalletti's team.
Paddy Agnew reports on the difficult decison facing Roma concerning the future of the iconic Francesco Totti.
With a Champions League tie against Bayern Munich looming, Juventus could be forgiven for taking their eye off the ball against Bologna.
Juventus left it late but they are back where many expected them to be at the start of the season: top of the pile.
Paddy Agnew looks ahead to the game everyone in Italy is talking about.
The Milan clubs have fallen off the pace and the league now looks to be a two-horse race between leaders Napoli and champions Juventus.
Genoa coach Gian Piero Gasperini has made a stand against the Genoa ultra who had called for him and the club's owner to go.
Napoli are the unofficial 'winter champions in Italy', but Juventus' form suggests they should be regarded as the favourites to retain their title.
A mixed year for Italian football, with bankruptcy and match fixing sharing the headlines with some hugely encouraging performances in Europe.
Only four points separate the top five clubs in what is the most exciting Serie A title race in many years.