Asian Football Confederation president Mohamed bin Hammam said the plan to take Premier League matches overseas was “not a good idea” and called for the idea to be rejected.
The Premier League has proposed playing matches at five different venues outside England from 2011.
Asian cities suggested as possible venues include Bangkok, Beijing, Hong Kong, Singapore as well as Melbourne that now falls under the jurisdiction of the AFC.
“With relation to the overall principle, it is my belief that it is not a good idea to organise domestic leagues in other territories other than their own,” bin Hammam said in a statement to AFP.
“If this principle is accepted, then the FA Premier League must accept reciprocal arrangements within their own territory.
“Saying that, my recommendation to the AFC Executive Committee would be to reject any initiatives of this nature.
“And we would urge the AFC member associations to protect their own national leagues and clubs within their territories. This is our position.”
English media and supporters groups have also flayed the proposals but influential figures within English football, including Arsenal boss Arsene Wenger, have welcomed the initiative.
Premier League chief executive Richard Scudamore has recommended adding a 39th fixture to the English season, estimating that the clubs could generate more than £5m each for the match.