Two in-form teams in Italy face each other, while in England, Jurgen Klopp takes charge of Liverpool for the first time.
Can Fiorentina maintain their winning run?
Six wins on the trot for table-topping Fiorentina, but on Sunday they travel south to face a rapidly improving Napoli side, who themselves are unbeaten in the league since the opening weekend of the season. The fixture could well shed light on the title credentials of both clubs.
Can Werder Bremen stop Robert Lewandowski?
Twelve goals in seven matches so far this season has made Bayern Munich striker Robert Lewandowski not only the form striker in Germany, but also across the whole of Europe. Werder Bremen are the opponents this week and they will have their work cut out stopping a striker who has converted 38.7 per cent of the chances that have come his way this season – the highest conversion record in Europe.
Can Celta Vigo preserve their unbeaten record?
Only two teams remain unbeaten in Spain’s top flight, one of which is Real Madrid, the other being Celta Vigo. Eduardo Berizzo’s side have an early start on Sunday morning as they have an 11am kick-off at league leaders’ Villarreal.
Can Jurgen Klopp get off to a winning start?
Jurgen Klopp’s Liverpool managerial career kicks off with a potentially tricky trip to in-form Tottenham. It’s not been the most propitious of starts for the German, who has already lost Joe Gomez and Danny Ings for the season without a ball kicked in anger.
Who will prevail in the Moscow derby?
Fourth placed Spartak host second placed Lokomotiv in one of this season’s Moscow derby matches. The game will take place at the recently completed Otkrytiye Arena, a venue constructed with the 2018 World Cup in mind, but which marks the first purpose-built stadium in Spartak’s history.