Group B – Kick-off 19:45 (BST)
Wolfsburg know that victory against Manchester United would take the German champions into the first knockout round and coach Armin Veh fancies their chances against the injury-hit visitors.
Wolfsburg will progress from Group B provided they do not secure fewer points in this game than CSKA Moscow pick up at Besiktas, while United – who are through but still need a draw to be guaranteed first place – have travelled without 14 regular players.
“We have a great opportunity to reach the last 16,” said Veh. “We have a home game in a full stadium against a United B team. Whether this is an advantage or a disadvantage at the moment, I cannot tell you.
“In Manchester, we played against the first team and performed very well and were unlucky to lose. We will do our best to reach the last 16. For us, this would be a huge success. We are playing very attractive football and are highly motivated and fit.
“We go into the game with passion and discipline. We have played very well so far in the Champions League, except for the second half in Moscow. I am very confident.
Manchester United manager Sir Alex Ferguson is having to contend with a lenghty injury list which has deprived him of his entire backline.
“There’s no good news with all these injured players,” he said. “We have left several players behind and we have a lot of thinking to do about team selection. That’s going to be very important.
“As we’ve explained, with Rio Ferdinand we have no scheduled return date yet. Wes Brown has a hamstring strain. We hope to have him fit for Saturday but you have to be careful with hamstring injuries. And John O’Shea and Jonny Evans are both out until January.
“They’re out for a few weeks. I think it’s a great game for Wolfsburg. Wolfsburg will be happy that we have so many injured players. Whether we are first or second in the group is not so important. The main thing is that some of the injured players will be fit again for the Premier League at the weekend.
“I am in Wolfsburg for the first time: I didn’t know the city before. That they have become German champions is phenomenal. This small town has done a wonderful thing.”