Ronald Koeman signed a two and a half-year deal to coach Valencia after resigning as PSV Eindhoven manager earlier this week.
The 44-year-old former Barcelona player replaces Quique Sanchez Flores who was sacked following Sunday’s 3-0 defeat at Sevilla.
“We wanted to sign an internationally recognised coach,” said Valencia president Juan Soler.
“We are convinced we will be in very good hands. He knows what Valencia’s objectives are, he knows the squad and he will bring us the success we want.”
Koeman will be joined by his assistant Tonny Bruins Slot, who also previously worked under Johan Cruyff at Barcelona.
Caretaker coach Oscar Fernandez will be in charge for Saturday’s match at Real Mallorca but Koeman will replace him for Tuesday’s visit of Rosenborg in the Champions League.