Juventus have received a setback on the eve of their Champions League clash with Manchester United, with the news that Mark Iuliano and Igor Tudor have been ruled out of the Old Trafford encounter.

Croation international Tudor has been suffering from ankle injury while Iuliano has flu. The pair are joined on the sidelines by striker Alessandro Del Piero who is expected to be out for several weeks.

With United and Juventus face each other twice in the space of the next week, with both fixtures likely to be crucial in deterrmining which teams reach the last 8